Reseveratrol and Rosiglitazone regulation of subcutaneous tissue gene expression in ZDF rats

The goal of this work was to examine if reserveratrol or rosiglitazone treatment could improve the metabolic status of obese male ZDF rats after 6 weeks. Gene expression was analyzed in several key metabolic tissues, including liver, various white adipose tissue depots, red tibalus muscle, and peripheral blood mononuclear cells.本研究旨在考察白藜芦醇（resveratrol）或罗格列酮（rosiglitazone）干预6周后，能否改善肥胖雄性ZDF大鼠的代谢状态。研究人员对肝脏、多种白色脂肪组织储库、红肌型胫骨肌以及外周血单个核细胞（Peripheral Blood Mononuclear Cells）等关键代谢组织中的基因表达水平进行了分析。