ECM_Proteins_PeptideData.xlsx

This is a proteomics set consisting of peptides identified to proteins (using Uniprot) that are related to extracellular matrix proteins. The objective of the experiment was to evaluate the effect of two spinal cord stimulation (SCS) treatments on the ECM-related protein expression levels in the ipsilateral dorsal quadrant of stimulated spinal cord (L1-L2 vertebral level) of animals that were subjected to the spared nerve injury (SNI) model of neuroptahic pain. Proteomics were performed by Cell Signaling Techology (Danvers, MA, USA). Data from four experimental groups were compared. The two SCS treatments groups (DTM and LR), a treatment sham group (No-SCS) and a group of uninjured animals (No-SNI). Protein was extracted from tissues and triptic peptides tagged using a TMT 10-plex system. They were run in parallel with other samples not relevant to this study. A tagged-peptide mix was used in the spectral runs for internal control. The data set contains the gene name, protein short name, protein description and the normalized signal to noise for each of the peptide's mass spectral peak.