The RIG-I-like receptors (RLRs: RIG-I, MDA5 and LGP2) trigger inflammatory and antiviral responses by sensing non-self RNA molecules produced during viral replication. LGP2 regulation of RIG-I and MDA

NIAID Data Ecosystem30

The influence of high salt on IFN-I-induced antiviral proteins

病毒免疫调节

免疫代谢

High salt diets have recently been implicated in hypertension, cardiovascular disease and autoimmune disease. However, whether and how dietary salt affects host antiviral response remain elusive. Here

NIAID Data Ecosystem20

Additional file 5 of Identification and integrated analysis of lncRNAs and miRNAs in IPEC-J2 cells provide novel insight into the regulation of the innate immune response by PDCoV infection

病毒免疫调节

miRNA靶标预测

Additional file 5. Prediction results of the target genes of DEmiRNAs.

Figshare2024-02-16 更新70

Role of PKR and Type I IFNs in Viral Control during Primary and Secondary Infection

病毒免疫调节

疫苗免疫机制

Type I interferons (IFNs) are known to mediate viral control, and also promote survival and expansion of virus-specific CD8+ T cells. However, it is unclear whether signaling cascades involved in elic

NIAID Data Ecosystem20

Cytoplasmic PARP1 links the genome instability to the inhibition of antiviral immunity through PARylating cGAS

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