Crystal structure of pyrimidine amide 11 bound to Lck
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Crystal structure of pyrimidine amide 11 bound to Lck Descriptor: N-[5-({[2-fluoro-3-(trifluoromethyl)phenyl]amino}carbonyl)-2-methylphenyl]-4-methoxy-2-[(4-piperazin-1-ylphenyl)amino]pyrimidine-5-carboxamide, Proto-oncogene tyrosine-protein kinase LCK Authors: Huang, X. Deposit date: 2007-10-19 Release date: 2007-12-18 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.3 Å) Cite: N-(3-(phenylcarbamoyl)arylpyrimidine)-5-carboxamides as potent and selective inhibitors of Lck: structure, synthesis and SAR. Bioorg.Med.Chem.Lett., 18, 2008
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2007-10-19
