Melanoma tumor antigen p97 or melanotransferrin (MTf) is an iron (Fe)-binding protein with high homology to serum transferrin. MTf is expressed at very low levels in normal tissues and in high amounts

NIAID Data Ecosystem20

CPSF6 regulates alternative polydenylation and proliferation of cancer cell through phase separation Ⅱ. CPSF6 regulates alternative polydenylation and proliferation of cancer cell through phase separation Ⅱ

RNA加工调控

癌细胞增殖

To verify the effect of phosphorylation of CPSF6 by CLK2 on APA, we co overexpressed CLK2 and wild-type CPSF6 or phosphorylated mutant CPSF6 in HEK293T cells Overall design: Compare the changes in APA

NIAID Data Ecosystem80

Transcriptional circuitry of NKX2-1 and SOX1 defines a previously unrecognized lineage subtype of small cell lung cancer to maintain neuroendocrine differentiation (RNA-Seq H187)

小细胞肺癌分子分型

神经内分泌分化

Molecular classification of small cell lung cancer (SCLC), a lethal and heterogeneous disease, was recently proposed based on expression of four lineage-defining transcription factors SCLC-A (ASCL1),

NIAID Data Ecosystem60