RNAseq analysis of integrin Ã3-mediated responses to in vitro docetaxel in 4T1 breast cancer cells
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资源简介：
We sought to transcriptomically characterize the effect of integrin Ã3 expression on breast cancer cell responses to the microtubule-inhibiting chemotherapeutic agent docetaxel. Experiments were performed in 4T1 murine breast cancer cells with or without CRISPR mediated deletion of the Itgb3 gene. Overall design: mRNA profiles from Ã3WT and Ã3KO 4T1 murine breast cancer cells after 24 hours of treatment with either DMSO or 10nM docetaxel and 48 hours of rest in fresh media. 3 biological replicates per group.
创建时间：
2021-05-14
