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Syndecan-1 inhibition promotes anti-tumor immune response and facilitates the efficacy of anti-PD1 checkpoint immunotherapy (kdSdc1 and mutant)

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP486952
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To investigate the function of SDC1 in the regulation of anti-tumor immunity, we established B16 and MC38 cell lines in which sdc1 or control RNA has been knocked down by shRNA. Overall design: Comparative gene expression profiling analysis of RNA-seq data for B16 and MC38 cell lines representing sdc1 knockdown, sdc1 knockdown+c30 mutant, sdc1 knockdown+ect mutant, sdc1 knockdown+sdc1 wt, that were stimulated with IFNr.
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2024-09-19
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