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Structure of human RIPK1 kinase domain in complex with compound 11

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Protein Data Bank Japan2024-03-13 更新2026-03-21 收录
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Structure of human RIPK1 kinase domain in complex with compound 11 Descriptor: (5R)-5-methyl-N-[(3S)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-4,5,6,7-tetrahydro-2H-indazole-3-carboxamide, Receptor-interacting serine/threonine-protein kinase 1 Authors: Fong, R, Lupardus, P.J. Deposit date: 2019-02-05 Release date: 2019-05-01 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Potent and selective inhibitors of receptor-interacting protein kinase 1 that lack an aromatic back pocket group. Bioorg.Med.Chem.Lett., 29, 2019

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2019-02-05
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