NF1 mutation drives neuronal activity-dependent optic glioma initiation

The study investigates the role of NF1 mutation and neuronal activity on the initiation of optic pathway glioma, a type of low-grade glioma. the RNAseq dataset investigates mRNA expression profile of human pilocytic astrocytomas (WHO grade I) Overall design: mRNA profiling of human non-neoplastic brains, NF1-associated pilocytic astrocytomas, and sporatic pilocytic astrocytomas