Multi-ancestry GWAS of age-related hearing loss identifies 140 loci and key cellular mechanisms

The dataset comprises summary statistics from the cross-ancestry meta-GWAS of Trpchevska et al. and De Angelis et al., the VA Million Veteran Program Consortium (MVP) and Biobank Japan (BBJ) on age-related hearing loss. Phenotype of ARHL was established using ICD diagnoses and self-reported hearing loss. The study comprised 456,413 cases and 1,053,834 controls of European, East Asian, African and Admixed American populations. Dataset columns: CHR, chromosome POS, genomic position (hg19) SNP, rsID A1, effect allele A2, other allele freq, effect allele frequency beta, effect size for A1 SE, standrad error of beta p, corresponding p-value for meta-analysis HetISq, HetChiSq and HetPVal, heterogeneity and corresponding p-values across studies N, sample size