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Promoter context-specific positive and negative transcriptional regulation of Glucocorticoid Receptor target genes by coregulator G9a

ChEBI2012-11-02 更新2026-07-21 收录

糖皮质激素受体调控

表观遗传转录调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-35962 数据链接链接失效反馈

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Promoter context-specific positive and negative transcriptional regulation of Glucocorticoid Receptor target genes by coregulator G9a

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创建时间：

2012-11-02

糖皮质激素受体调控

乳腺细胞基因表达

To further characterize the role of the unliganded glucocorticoid receptor (GR) in breast cells, we used an shRNA vector directed against GR to create EPH-4 mouse mammary cell lines with depleted endo

NIAID Data Ecosystem90

BRD4-PRC2 Represses Transcription of T-helper 2-Specific Negative Regulators during T-cell Differentiation

Th2细胞分化

表观遗传转录调控

BRD4 is a well-recognized transcriptional activator, but how it regulates gene transcriptional repression in a cell-type specific manner has remained elusive. In this study, we report that BRD4 works

NIAID Data Ecosystem60

Gene expressions regulated by N/C interacting and non-interactiong GR. Chlorocebus aethiops

糖皮质激素受体调控

基因表达谱分析

Glucocorticoid receptor (GR) was demonstrated to undergo an N/C interaction between the 26VMDFY30 motif in the N-terminus and C-terminal LBD in the presence of its co-chaperone cytoplasmic constitutiv

NIAID Data Ecosystem40

BAP1 complex promotes transcription by opposing PRC1-mediated H2A ubiquitylation

表观遗传转录调控

BAP1去泛素化与基因激活

In Drosophila, a complex consisting of Calypso and ASX catalyzes H2A deubiquitination and has been reported to act as part of the Polycomb machinery in transcriptional silencing. The mammalian homolog

NIAID Data Ecosystem70

Circularized chromosome conformation capture (4C-seq) in A549 and U2OS cells stably expressing rat GRα. Circularized chromosome conformation capture (4C-seq) in A549 and U2OS cells stably expressing rat GRα

4C-seq染色质构象分析

糖皮质激素受体调控

To investigate the interaction landscape at the GILZ locus we performed 4C-seq in A549 (ATCC CCL-185) and U2OS cells stably expressing rat GRα (Rogatsky et al. , Mol Cell Biol, 1997. 17(6): p. 3181-93

NIAID Data Ecosystem40

Promoter context-specific positive and negative transcriptional regulation of Glucocorticoid Receptor target genes by coregulator G9a

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