Cys285Ser mutant PPARgamma ligand-binding domain complexed with 15-deoxy-delta12,14-prostaglandin J2

Cys285Ser mutant PPARgamma ligand-binding domain complexed with 15-deoxy-delta12,14-prostaglandin J2 Descriptor: (5E,14E)-11-oxoprosta-5,9,12,14-tetraen-1-oic acid, Peroxisome proliferator-activated receptor gamma Authors: Waku, T, Oyama, T, Shiraki, T, Morikawa, K. Deposit date: 2008-11-19 Release date: 2009-10-06 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Atomic structure of mutant PPARgamma LBD complexed with 15d-PGJ2: novel modulation mechanism of PPARgamma/RXRalpha function by covalently bound ligands Febs Lett., 583, 2009