Data and code for: Changes to the mtDNA copy number during yeast culture growth

We show that the mtDNA copy number in growing cultures of the yeast Saccharomyces cerevisiae increases by a factor of up to 4, being lowest (~10 per haploid genome) and stable during rapid fermentative growth, and highest at the end of the respiratory phase. When yeast are grown on glucose, the onset of the mtDNA copy number increase coincides with the early stages of the diauxic shift, and the increase continues through respiration. A lesser yet still substantial copy number increase occurs when yeast are grown on a nonfermentable carbon source, i.e. when there is no diauxic shift. The mtDNA copy number increase during and for some time after the diauxic shift is not driven by an increase in cell size. The copy number increase occurs in both haploid and diploid strains, but is markedly attenuated in a diploid wild isolate that is a ready sporulator. Strain-to-strain differences in mtDNA copy number are least apparent in fermentation and most apparent in late respiration or stationary p..., , , , # Data from: Changes to the mtDNA copy number during yeast culture growth

Royal Society Open Science, 2022
([https://doi.org/10.1098/rsos.211842](https://doi.org/10.1098/rsos.211842))
============================================================================

## Author/Principal Investigator Information

Name: Ben Galeota-Sprung
ORCID: 0000-0003-0085-0948
Institution: University of Pennsylvania
Address:
Email: [[e-mail]](mailto:[e-mail])

# SHARING/ACCESS INFORMATION

* Licenses/restrictions placed on the data: None
* Links to publications that cite or use the data: [https://doi.org/10.1098/rsos.211842](https://doi.org/10.1098/rsos.211842)
* Recommended citation for this dataset: [https://doi.org/10.1098/rsos.211842](https://doi.org/10.1098/rsos.211842)

# DATA & FILE OVERVIEW

## File List

### The following files are the *raw* data for the image-based assessment of cell size over time presented in Fig. S7 C,D,E

* `images.zip`: this archive unpacks to several PNG ...