Yeast RNA polymerase II initiation factor e: isolation and identification as the functional counterpart of human transcription factor IIB.
收藏PubMed Central1992-12-01 更新2026-05-16 收录
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https://pmc.ncbi.nlm.nih.gov/articles/PMC50536/
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资源简介：
Yeast RNA polymerase II initiation factor e was purified to homogeneity and identified by biochemical criteria as the counterpart of human transcription factor IIB. Factor e was essential for initiation of transcription from yeast and mammalian promoters in a reconstituted yeast transcription system. Activity resided in a single polypeptide of approximately 41 kDa, identified by peptide sequence analysis as the product of the SUA7 gene. Factor e interacted specifically with RNA polymerase II, consistent with a proposed role in determining the start site of transcription. IMAGES:
提供机构：
National Academy of Sciences
创建时间：
1992-12-01
