Estimated lower-bounds of fold resistance against NVP exerted by single amino acid substitutions in the distinct genetic background of the baseline isolates.
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Values indicated are medians of all parameter estimates and the 5th and 95th percentile of the estimates are indicated in brackets. 'n.s’ means ‘not selected’ and n.i. means parameter ‘not identifiable’. Parameters FR(69I), FR(103N), FR(122K), FR(128Q), FR(208Y) and FR(218G) were not identifiable from the data for any isolates and thus omitted from the table.
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2015-12-02
