Crystal Structure of the first bromodomain of human BRD4 in complex with a 3,5-dimethylisoxazol ligand
收藏Protein Data Bank Japan2023-09-20 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/4j0s
下载链接
链接失效反馈官方服务：
资源简介：
Crystal Structure of the first bromodomain of human BRD4 in complex with a 3,5-dimethylisoxazol ligand Descriptor: 1,2-ETHANEDIOL, 3-(3,5-dimethyl-1,2-oxazol-4-yl)-5-[(S)-hydroxy(phenyl)methyl]phenol, Bromodomain-containing protein 4 Authors: Filippakopoulos, P, Picaud, S, Qi, J, Felletar, I, Hewings, D.S, von Delft, F, Conway, S.J, Bountra, C, Arrowsmith, C.H, Edwards, A, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2013-01-31 Release date: 2013-02-13 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.84 Å) Cite: Optimization of 3,5-dimethylisoxazole derivatives as potent bromodomain ligands. J.Med.Chem., 56, 2013
创建时间：
2013-01-31
