Taking advantage of an in situ nucleosome stability assay based on the exposure of agarose-embedded nuclei to a concentration series of salt we could distinguish H2A.Z-nucleosomes at transcription sta

DataCite Commons2025-06-06 更新40

Transcriptional consequences of DNA gyrase inhibition . Escherichia coli

转录调控机制

DNA拓扑结构

DNA gyrase is an essential enzyme whose activity is required for DNA replication and chromosome maintenance. Inhibition of gyrase results in multiple physiological effects including changes in DNA sup

NIAID Data Ecosystem30

MYC assembles and stimulates topoisomerases 1 & 2 in a “topisome” [ChIP-seq]

基因表达调控

DNA拓扑结构

High-intensity transcription and replication supercoil DNA to levels that can impede or halt these processes. As a potent transcription amplifier and replication accelerator, the proto-oncogene MYC mu

NIAID Data Ecosystem50

Loop-extruding Smc5/6 organizes transcription-induced positive DNA supercoils.. Loop-extruding Smc5/6 organizes transcription-induced positive DNA supercoils.

DNA拓扑结构

转录调控

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem40