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The transcription factor IRF4 regulates the differentiation and function of intestinal ILC3s

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NIAID Data Ecosystem2026-05-02 收录
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To investigate the role of IRF4 in the regulation of ILC3 development and function, we used the wildtype mice as control and carried out single-cell RNA sequencing (BD Rhapsody) on gut ILC3s. ILC3s from Irf4flox/floxRorccre and Irf4flox/flox mice were isolated from the small intestine and analyzed by cleavage under targets and tagmentation (CUT&Tag).

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2025-07-10
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