Functional dissection of Bmi1 independence of MN1 leukemia
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE50877
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资源简介：
MN1 leukemia is a poor prognosis leukemia occuring as MN1 overexpression or fusion with TEL (MN1-TEL), MN1 and MN1-TEL show different biology in terms of dependence of known self-renewal associated genes in leukemia, c-kit positive murine primary bone marrow cells were retrovirally transduced with MN1, MN1-TEL or MN1-TEL mutant MN1-TELdelDBD showing biological similarity with MN1, after retroviral transformation of cells and 10 d culture RNA was extracted and gene expression profiling was assessed 3 samples with 3 replicates each sample: gene expression array comparing expression profiles of MN1, MN1-TEL and MN1-TEL del DBD trasformed murine c-kit+ bone marrow cells
创建时间：
2019-01-16
