Pharmacodynamic parameter estimates and confidence interval for the final model and Bootstrap (1000 simulations) for patient state index (PSI) and suppression ratio (SR).
BackgroundA target AUC0-24/MIC ratio of 400 has been associated with its clinical success when treating Staphylococcus aureus infections but is not currently supported by state-of-the-art evidence-bas
Context: Kinetic models could assist clinicians potentially in managing cases of lead poisoning. Several models exist that can simulate lead kinetics but none of them can predict the effect of chelati
Overall, UTI-related, and all-cause HRU outcomes of uUTI outpatients stratified by inappropriate/suboptimal antibiotic prescription (Part A) and antibiotic switching (Part B) during 12-month follow-up
Trials of the early bactericidal activity (EBA) of tuberculosis (TB) treatments assess the decline, during the first few days to weeks of treatment, in colony forming unit (CFU) count of Mycobacterium