Crystal structure of the cAMP-dependent protein kinase A cocrystallized with PKI (5-24). Soaking of aminofasudil and displacing it with the fragment isoquinoline.
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Crystal structure of the cAMP-dependent protein kinase A cocrystallized with PKI (5-24). Soaking of aminofasudil and displacing it with the fragment isoquinoline. Descriptor: ISOQUINOLINE, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha Authors: Oebbeke, M, Gerber, H.-D, Heine, A, Klebe, G. Deposit date: 2020-04-16 Release date: 2021-04-28 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Fluorescence-based displacement experiments To Be Published
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2020-04-16



