MRI findings in striatal stroke patients and control stroke patients.

Clear evidence of a secondary lesion is denoted by “+”. “++” denotes especially large secondary lesions. Patients 1 through 12 showed clear evidence for delayed midbrain changes (DWI and T2) in ipsilateral substantia nigra occurring between days 6 and 10. Despite heavy motion artifacts, scans of patients 13 through 15 still showed some evidence for secondary midbrain changes (+). Several patients missed scans (n.d.). The primary reason for this was that patients had either been transferred to a rehabilitation center or discharged. Control stroke patients (patients 17 through 20) did not show evidence of secondary midbrain changes. Note that cortical involvement or the overall size of the infarct did not affect the development of secondary midbrain changes. Normalization of ADC was observed at late measurements in single patients (days 72, 90, and 144).MRI findings in striatal stroke patients and control stroke patients.