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资源简介：
m6A promotes DNA replication progression
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创建时间：
2023-06-19
相关数据集
RNA-seq and ribosome profiling of heat shocked wild type and Mettl14 -/- mouse embryonic stem cells. RNA-seq and ribosome profiling of heat shocked wild type and Mettl14 -/- mouse embryonic stem cells
N6-methyladenosine (m6A) is a dynamic and reversible nucleotide modification in mRNA. m6A alters mRNA fate, but it is unclear why the effects of m6A can vary in different cellular contexts. Here we sh
NIAID Data Ecosystem50
MeRIPseq of m6A in HeLa synchonized cells with total RNA
MeRIPSeq of HeLa cells synchronized by a double thymidine block to obtain the cell cycle phases and work with total RNA to study m6A mark in mRNA without polyA tail RNA seq of HeLa cells synchronized
NIAID Data Ecosystem10
Analysis of the genes with unique m 6 A peak in KU80 and down-regulated expression in Δ CpMTA1 , or up-regulated expression in Δ CpMTA1 .
Analysis of the genes with unique m6A peak in KU80 and down-regulated expression in ΔCpMTA1, or up-regulated expression in ΔCpMTA1.
NIAID Data Ecosystem00
Identification of cis elements for temporal and spatial control of DNA replication [4C-seq]
DNA replication occurs in units of chromatin higher order organization (Topologically Associating Domains, or TADs; replication domains, or RDs), which self-organize in 3D into sub-nuclear compartment
NIAID Data Ecosystem30
Marker frequency at head-on or co-directional gene regions
This study demonstrates that R-loops formed at head-on oriented genes block DNA replication in the absence of RNaseHIII.
NIAID Data Ecosystem00
