Microarray analysis of lncRNA and mRNA expression profiles in sinonasal inverted papilloma

To explore the expression profile, potential functions, and diagnostic and clinicopathological significance of lncRNAs in sinonasal inverted papilloma (SNIP).The expression profiles of lncRNAs and mRNAs were analyzed using a microarray. The potential functions and clinical implications of specific lncRNAs were further analyzed by bioinformatics and statistical methods. SNIP tissue samples were obtained from 4 patients with SNIP.The diagnosis of SNIP was confirmed by histopathological examination.A total of 12 patients with only nasal septum deviation were selected to provide nasal mucosal tissue samples as the control group.