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RNA-seq analysis of peripheral nerve with conditional knockout of H3K27 demethylases.

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https://www.ncbi.nlm.nih.gov/sra/SRP325543
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The goal of the experiment was to determine the role of H3 emethylases in the nerve injury response in peripheral nerve. A Schwann cell specific knockout of the H3K27 demethylases (Jmjd3 and Utx) was generated to compare with wild type mice in sham and injured mice at 1d and 7d timepoints after nerve injury. Overall design: For each condition, three independent biological replicates were prepared.
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2021-06-27
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