Comparative genome analysis of Legionella pneumophila novel sequence types ST2858 and ST378

Cases of Legionnaires disease caused by Legionella pneumophila serogroup 1 sequence type (STs) ST2858 and ST378 were detected in Montreal, Canada. In total, 67 isolates were subjected to whole genome sequencing (WGS) in this study. Ten of these were clinical ST2858 isolates collected between 2018-2021. The ST378 isolates included in this analysis come from 8 clinical samples and 43 environmental samples, recovered between 2007 and 2021. We performed comparative genome analysis to determine the genetic diversity and source of the ST.