Dataset for "Relationship between change in social evaluation learning and mood in early antidepressant treatment: A prospective cohort study in primary care"

This study aimed to examine the association between change in social evaluation learning and mood over the first eight weeks of antidepressant treatment. Participants were primary care patients receiving antidepressant treatment under the care of their GP. Participants completed data collection at five timepoints; baseline (prior to starting antidepressants or within the first two weeks of treatment), two week, six week, eight week and six-month follow-up. At each testing session participants completed self-report measures of depression (BDI-II, PHQ-9), anxiety (GAD-7), and a computerised task measuring learning of social evaluations about the self, a friend and a stranger.

Prior to the COVID-19 pandemic participants also completed three other cognitive tasks (associative learning, word categorisation and recall, and a facial emotion recognition task). To reduce fatigue effects associated with remote testing we removed these tasks from March 2020. Due to only a small number of participants completing these measures we have not analysed this data and have therefore not reported results in the associated paper. However, we have made the data open access to allow for exploratory research in preparation for potential future studies. Full details of these tasks are available in supplementary materials in the manuscript reporting our main findings.

本研究旨在探讨社会评价学习变化与抗抑郁治疗首八周情绪变化之间的关系。受试者为接受初级保健医生照料的正在接受抗抑郁治疗的门诊患者。受试者在五个时间点完成了数据收集：基线（在开始服用抗抑郁药或治疗的前两周内）、两周、六周、八周以及六个月随访。在每次测试中，受试者完成了关于抑郁（BDI-II，PHQ-9）、焦虑（GAD-7）的自我报告量表，以及一项测量关于自我、朋友和陌生人的社会评价学习的计算机化任务。在COVID-19大流行之前，受试者还完成了三项其他认知任务（联想学习、词汇分类和回忆，以及面部情绪识别任务）。为了减少远程测试带来的疲劳效应，我们从2020年3月起移除了这些任务。由于只有少数受试者完成了这些测量，我们未对这些数据进行分析，因此未在相关论文中报告结果。然而，我们已将数据设置为开放获取，以便为可能的未来研究进行探索性研究。关于这些任务的详细信息可在报告主要发现的论文的补充材料中找到。