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The transcription factor DUX4 orchestrates translational reprogramming by broadly suppressing translation efficiency and promoting expression of DUX4-induced mRNAs

NIAID Data Ecosystem2026-05-01 收录

DUX4翻译重编程

翻译效率调控

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE206439 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2023-09-01

病毒-宿主相互作用

翻译效率调控

Supplementary Material 7: Supplementary Table S1. RNA-seq raw counts from this study, related to Fig. 2. Columns A-E contain gene information. Columns F-K mock-infected and columns L-Q RSV-infected ra

Figshare2025-07-15 更新50

Data_Sheet_2_Sox9 Determines Translational Capacity During Early Chondrogenic Differentiation of ATDC5 Cells by Regulating Expression of Ribosome Biogenesis Factors and Ribosomal Proteins.xlsx

软骨细胞分化

翻译效率调控

IntroductionIn addition to the well-known cartilage extracellular matrix-related expression of Sox9, we demonstrated that chondrogenic differentiation of progenitor cells is driven by a sharply define

NIAID Data Ecosystem40

Profiling transcriptional and translational response to anoxia or hypoxia of genes in DNA damage response and repair pathways in human fibroblast and prostate cancer cells using NanoString nCounter.

低氧应激与DNA损伤修复

翻译效率调控

Identification of genes in DNA damage response and repair pathways differentially transcribed or translated under anoxia or hypoxia in GM05757 normal human fibroblast cells and DU145 human prostate ca

NIAID Data Ecosystem30

Translation Levels Control Multi-Spanning Membrane Protein Expression

膜蛋白表达优化

翻译效率调控

Attempts to express eukaryotic multi-spanning membrane proteins at high-levels have been generally unsuccessful. In order to investigate the cause of this limitation and gain insight into the rate lim

Figshare2016-01-19 更新50

PABPN1 effect on translation efficiency.

翻译效率调控

细胞基因表达

The effect of PABPN1 on translation efficiency was assessed using RNA sequencing of polysomal fractions from muscle cells: parental vs. cells with stable PABPN1 down-regulation (shPAB). The library wa

NIAID Data Ecosystem30

The transcription factor DUX4 orchestrates translational reprogramming by broadly suppressing translation efficiency and promoting expression of DUX4-induced mRNAs

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