Crystal structure of the kinase domain of human RIPK2 in complex with the activation loop targeting inhibitor CS-R35
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Crystal structure of the kinase domain of human RIPK2 in complex with the activation loop targeting inhibitor CS-R35 Descriptor: 2-[2-fluoranyl-4-[[2-fluoranyl-4-[2-(methylcarbamoyl)pyridin-4-yl]oxy-phenyl]carbamoylamino]phenyl]sulfanylethanoic acid, Receptor-interacting serine/threonine-protein kinase 2 Authors: Pinkas, D.M, Bufton, J.C, Suebsuwong, C, Ray, S.S, Dai, B, Newman, J.A, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Degterev, A, Cuny, G.D, Bullock, A.N. Deposit date: 2017-10-19 Release date: 2018-02-21 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.38 Å) Cite: Activation loop targeting strategy for design of receptor-interacting protein kinase 2 (RIPK2) inhibitors. Bioorg. Med. Chem. Lett., 28, 2018
创建时间：
2017-10-19
