Genetic effects are often context-dependent, with the same genotype differentially affecting phenotypes across environments, life stages, and sexes. We used an environmental manipulation designed to i
Genome-wide association studies (GWAS) have identified more than 40 loci associated with Alzheimer’s disease (AD), but the causal variants, regulatory elements, genes and pathways remain largely unkno
We report the 5hmC in human hippocampus subject to normal aging and Alzheimer's disease. 5hmC-Seal in postmortal lateral temporal lobe of Alzheimer's disease affected brains (AD), control Old (Old) an
Genome-wide association studies (GWAS) have identified more than 40 loci associated with Alzheimer's disease (AD), but the causal variants, regulatory elements, genes and pathways remain largely unkno