EED in complex with a triazolopyrimidine
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EED in complex with a triazolopyrimidine Descriptor: GLYCEROL, N-(2,3-dihydro-1-benzofuran-4-ylmethyl)-8-(4-methylsulfonylphenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine, N-[(5-fluoranyl-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(2-methylpyridin-3-yl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine, ... Authors: Read, J.A. Deposit date: 2020-04-28 Release date: 2021-05-12 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.84 Å) Cite: Free energy perturbation in the design of EED ligands as inhibitors of polycomb repressive complex 2 (PRC2) methyltransferase. Bioorg.Med.Chem.Lett., 39, 2021
创建时间：
2020-04-28
