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Genome-wide maps of chromatin state in Ad-ube3b and control lymphoma cells

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NIAID Data Ecosystem2026-04-25 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP186267
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资源简介:
We report the application of single-molecule-based sequencing technology for high-throughput profiling of p-RNAPII(ser2) with promoters in mammalian cells. We performed ChIP sequencing with antibody to total p-RNAPII(ser2) in UBE3B overexpression and control group. Inspection of multiple individual traces and global analyses showed that UBE3B overexpression globally reduced association of p-RNAPII(ser2) with promoters. Overall design: We performed ChIP sequencing with antibody to total p-RNAPII(ser2) in UBE3B overexpression and control group and globally analysed association of p-RNAPII(ser2)with promoters.
创建时间:
2020-12-23
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