DDX1-Mediated mitochondrial DNA G-quadruplex Resolution Is Essential for Hematopoietic Stem Cell Homeostasis and Radioresistance
收藏国家人口健康科学数据中心2026-06-01 收录
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https://www.ncmi.cn/phda/dataDetails.do?id=CSTR:17970.11.A001G.202601.22.V1.0
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Sorted CD34+ hematopoietic stem cells (HSCs) were cultured overnight at 37°C in a humidified incubator with 5% CO₂. The cells were then exposed to 5 Gy X-ray irradiation and cultured for an additional 24 hours. For each experimental condition (irradiated and non-irradiated), 1*10^7 CD34+ HSCs were collected. Mitochondrial proteins were extracted using the Mitochondrial Protein Extraction Kit (Beyotime, Cat. No. C3601). Subsequent LC-MS/MS analysis, sequence database searching, and bioinformatics analyses were conducted by Bioprofile Co., Ltd.
提供机构：
北京蛋白质组研究中心
创建时间：
2024-11-21
