five

Asymmetric Synthesis of 2‑Substituted Azetidin-3-ones via Metalated SAMP/RAMP Hydrazones

收藏
NIAID Data Ecosystem2026-03-09 收录
下载链接:
https://figshare.com/articles/dataset/Asymmetric_Synthesis_of_2_Substituted_Azetidin-3-ones_via_Metalated_SAMP_RAMP_Hydrazones/3546744
下载链接
链接失效反馈
官方服务:
资源简介:
2-Substituted azetidin-3-ones can be prepared in good yields and enantioselectivities (up to 85% ee) by a one-pot procedure involving the metalation of the SAMP/RAMP hydrazones of N-Boc-azetidin-3-one, reaction with a wide range of electrophiles, including alkyl, allyl, and benzyl halides and carbonyl compounds, followed by hydrolysis using oxalic acid.
创建时间:
2016-08-29
二维码
社区交流群
二维码
科研交流群
商业服务