In vitro and in vivo consequences of inflammatory reguloation of Nonsense-mediated RNA decay pathway for pancreatic beta-cell function and viability
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https://www.ncbi.nlm.nih.gov/sra/SRP415292
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资源简介:
Ghiasi SM, et al., 2023: Proinflammatory cytokines are implicated in pancreatic beta-cell failure in type 1 and type 2 diabetes and are known to stimulate alternative RNA splicing and the expression of Nonsense-Mediated RNA Decay (NMD) components. Here, we investigated whether cytokines would regulate NMD activity and identify transcript isoforms targeted in beta-cells.
创建时间:
2023-05-04



