Mycobacterium tuberculosis variant bovis Genome sequencing and assembly

Mycobacterium bovis bacillus Calmette-Guérin (BCG) is the only vaccine available against tuberculosis. This study reports the complete genome sequence of BCG Danish 1331 (07/270), one of the WHO reference reagents for BCG vaccines. Unexpected findings, including the presence a of DU1-like duplication in BCG Danish 1331 (07/270) and the absence of a DU1 in the Pasteur control strains, underline the importance of the genomic characterization of our BCG vaccine strains.