p53 cancer mutant Y220C in complex with compound MB710
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p53 cancer mutant Y220C in complex with compound MB710 Descriptor: 1,2-ETHANEDIOL, 2-(diethylamino)-6-iodanyl-5-oxidanyl-7-pyrrol-1-yl-1,3-benzothiazole-4-carboxylic acid, Cellular tumor antigen p53, ... Authors: Joerger, A.C, Baud, M.G.J, Bauer, M.R, Fersht, A.R. Deposit date: 2017-05-18 Release date: 2018-05-09 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Aminobenzothiazole derivatives stabilize the thermolabile p53 cancer mutant Y220C and show anticancer activity in p53-Y220C cell lines. Eur J Med Chem, 152, 2018
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2017-05-18
