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X-ray Structure of SARS-CoV main protease covalently modified by compound GRL-0686

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Protein Data Bank Japan2024-10-23 更新2026-03-28 收录
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X-ray Structure of SARS-CoV main protease covalently modified by compound GRL-0686 Descriptor: 3C-like proteinase, 5-chloropyridin-3-yl 1-(3-nitrobenzene-1-sulfonyl)-1H-indole-5-carboxylate, DIMETHYL SULFOXIDE Authors: Mesecar, A.D, Anson, B.A, Ghosh, A.K, Center for Structural Genomics of Infectious Diseases (CSGID) Deposit date: 2021-07-07 Release date: 2021-09-29 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.63 Å) Cite: Indole Chloropyridinyl Ester-Derived SARS-CoV-2 3CLpro Inhibitors: Enzyme Inhibition, Antiviral Efficacy, Structure-Activity Relationship, and X-ray Structural Studies. J.Med.Chem., 64, 2021

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2021-07-07
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