Original networks, NVC networks and COPD data sets used in: Enhancement of COPD biological networks using a web-based collaboration interface
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Original networks, NVC networks and their descriptions.The file contains the names of the original networks (as they were published), agglomerated NVC networks (as presented on the Bionet website), and network descriptions. The 15 networks that were discussed during jamboree are indicated by “X” in the column Discussed in Jamboree.
COPD data sets, their descriptions, and the comparisons used to build the COPD models during Phase 1.Reverse causal reasoning was performed using COPD and emphysema data sets from lung, small airway, and alveolar macrophages of early COPD patients and healthy smokers. Data Sets, the Gene Expression Omnibus (GEO) used to build the COPD networks. SCs, state changes defined using differentially expressed genes that meet the following criteria: FDR adjusted p
原始网络、NVC网络及其描述。该文件包含原始网络的名称(如原文所述)、在Bionet网站上展示的聚合NVC网络,以及网络描述。在集会期间讨论的15个网络在“集会讨论”列中用“X”标出。COPD数据集、其描述以及用于构建第一阶段COPD模型所采用的比较方法。采用COPD和肺泡巨噬细胞、小气道以及早期COPD患者的肺泡巨噬细胞数据集进行反向因果推理。用于构建COPD网络的基因表达综合数据库(GEO)。SCs,通过满足以下标准的差异表达基因定义的状态变化:调整后的FDR p值
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