1.8 Angstroms molecular structure of mouse liver glutathione S-transferase mutant C47A complexed with S-(P-nitrobenzyl)glutathione
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1.8 Angstroms molecular structure of mouse liver glutathione S-transferase mutant C47A complexed with S-(P-nitrobenzyl)glutathione Descriptor: Glutathione S-transferase P 1, S-(P-NITROBENZYL)GLUTATHIONE Authors: Canals, A, Coll, M. Deposit date: 2010-07-30 Release date: 2011-06-15 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.77 Å) Cite: Site-directed mutagenesis of mouse glutathione transferase P1-1 unlocks masked cooperativity, introduces a novel mechanism for 'ping pong' kinetic behaviour, and provides further structural evidence for participation of a water molecule in proton abstraction from glutathione. Febs J., 278, 2011
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2010-07-30
