Kinase domain of cSrc in complex with a substituted pyrazolopyrimidine
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Kinase domain of cSrc in complex with a substituted pyrazolopyrimidine Descriptor: 1-[(2R)-2-chloro-2-phenylethyl]-6-{[2-(morpholin-4-yl)ethyl]sulfanyl}-N-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Proto-oncogene tyrosine-protein kinase Src Authors: Richters, A, Rauh, D. Deposit date: 2013-12-17 Release date: 2015-03-04 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Combining X-ray Crystallography and Molecular Modeling toward the Optimization of Pyrazolo[3,4-d]pyrimidines as Potent c-Src Inhibitors Active in Vivo against Neuroblastoma. J.Med.Chem., 58, 2015
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2013-12-17
