KEGG pathway analysis of significantly altered metabolic pathways. This table presents KEGG pathway analysis based on metabolites identified as statistically significant (p < 0.05) through two-way ANOVA and ASCA, considering the effects of prognosis, sample collection time, and their interaction. However, no significant metabolic pathway alterations were found between the PS and Exitus groups. Therefore, no comparison between these groups was included in the table. Metabolic pathways significantly affected by differences in creatine or tyrosine levels across the different prognostic groups were also highlighted by double asterisks.

KEGG pathway analysis of significantly altered metabolic pathways. This table presents KEGG pathway analysis based on metabolites identified as statistically significant (p < 0.05) through two-way ANOVA and ASCA, considering the effects of prognosis, sample collection time, and their interaction. However, no significant metabolic pathway alterations were found between the PS and Exitus groups. Therefore, no comparison between these groups was included in the table. Metabolic pathways significantly affected by differences in creatine or tyrosine levels across the different prognostic groups were also highlighted by double asterisks.