A microglia-CD4+ T cell partnership generates protective anti-tumor immunity to glioblastoma [scRNA-seq]
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP440584
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资源简介：
The aim of the study is to analyze and compare the transcriptional profiles at a single cell resolution of tumor-infiltrating immune cells from healthy mouse brain as well as glioma brearing brain tissues treated with anti-CTLA4 in the presence or absence of CD4 T cells . Overall design: Single-cell RNA of all immune cells from healthy brain and Glioma-005 glioblastoma tumors treated with IgG, anti_CTLA4 and combination of anti_CTLA4 and anti_CD4 (depletion) were performed at Day 35 post implantation. Each sample is a pool of 3 tumor samples.
创建时间：
2025-02-26
