Crystal structure of KRAS G12C in complex with GNE-1952
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Crystal structure of KRAS G12C in complex with GNE-1952 Descriptor: 1-[4-[6-chloranyl-7-(5-methyl-1~{H}-indazol-4-yl)quinazolin-4-yl]piperazin-1-yl]propan-1-one, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... Authors: Oh, A, Tam, C, Wang, W. Deposit date: 2021-08-03 Release date: 2022-03-16 Last modified: 2024-12-25 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Conformation-locking antibodies for the discovery and characterization of KRAS inhibitors. Nat.Biotechnol., 40, 2022
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2021-08-03
