Modified Fast Aneuploidy Screening Test-Sequencing System (mFAST-SeqS) was applied to stratify samples based on their overall tumor fraction in cfDNA.EGA dataset EGAD00001006385
Massive parallel sequencing (MPS) was performed in comparison to the respective somatic genome of each animal. Copy number and structural aberrations were validated using digital droplet PCR (ddPCR).
BackgroundDiabetic kidney disease (DKD), one of the main complications of diabetes mellitus (DM), has become a frequent cause of end-stage renal disease. A clinically convenient, non-invasive approach
Here we sought to evaluate copy number landscape of metastatic PDAC through whole-genome sequencing of cfDNA and determine its clinical significance. In total, ninety plasma samples from 70 pancreatic