Crystal structure of EGFR T790M/C797S mutant in complex with brigatinib
收藏Protein Data Bank Japan2026-03-04 更新2026-04-19 收录
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Crystal structure of EGFR T790M/C797S mutant in complex with brigatinib Descriptor: 5-chloro-N~4~-[2-(dimethylphosphoryl)phenyl]-N~2~-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}pyrimidine-2,4-diamine, Epidermal growth factor receptor Authors: Kukimoto-Niino, M, Shirouzu, M. Deposit date: 2022-10-21 Release date: 2023-10-25 Last modified: 2026-03-04 Method: X-RAY DIFFRACTION (3.404 Å) Cite: A macrocyclic kinase inhibitor overcomes triple resistant mutations in EGFR-positive lung cancer. NPJ Precis Oncol, 8, 2024
创建时间：
2022-10-21
