Maternally deposited germline piRNAs silence the tirant retrotransposon in somatic cells

ChEBI2013-04-09 更新2026-07-21 收录

piRNA调控

转座子沉默机制

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Maternally deposited germline piRNAs silence the tirant retrotransposon in somatic cells

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2013-04-09

Piwi induces piRNA-guided transcriptional silencing and establishment of a repressive chromatin state

转座子沉默机制

染色质表观遗传调控

In the Metazoan germline, piwi proteins and associated piwi-interacting RNAs (piRNAs) provide a defense system against the expression of transposable elements. In the cytoplasm, piRNA sequences guide

NIAID Data Ecosystem120

Epigenomic conservation of transposable element silencing [ChIP-seq]. Epigenomic conservation of transposable element silencing [ChIP-seq]

转座子沉默机制

表观遗传修饰

Transposable elements (TEs) comprise a substantial proportion of primate genomes. Because of the potential deleterious effects of TEs during development, TEs are targeted for silencing by sequence-spe

NIAID Data Ecosystem70

De novo piRNA cluster formation in the Drosophila germline triggered by transgenes containing a transcribed transposon fragment

转座子沉默机制

piRNA生物合成

PIWI interacting RNAs (piRNAs) provide defense against transposable element (TE) expansion in the germline of metazoans. piRNAs are processed from the transcripts encoded by specialized heterochromati

NIAID Data Ecosystem40

Tdrd6a recruits Ziwi-bound piRNAs and coordinates deposition of germ plasm mRNAs into primordial germ cells [RIP-Seq]. Danio rerio

生殖细胞发育

piRNA调控

Germ plasm, the Balbiani body and nuage are evolutionary conserved structures essential for germ cell specification and maintenance. We describe Tdrd6a as a component of these structures with two dist

NIAID Data Ecosystem80

Additional file 2 of Dynamic co-evolution of transposable elements and the piRNA pathway in African cichlid fishes

转座元件

piRNA调控

Additional file 2. Table S1. Results of orthology analysis, PiggyBac-1 TIR BLASTN results, selection test results, and metadata on all the genomic resources used to ascertain presence/absence of piwil

Figshare2025-01-23 更新50

Maternally deposited germline piRNAs silence the tirant retrotransposon in somatic cells

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