Gene expression profiling in mice overexpressing human wild type (WT) keratin 8 (K8) or K8 variants (G62C and R341H).. Mus musculus

3 months old untreated male/female animals were used in the experiment. We used microarray analysis to determine differential gene expression in mice livers overexpressing WT K8 and K8 variants. Overall design: Mice liver tissues were used for RNA extraction and hybridization on Affymetrix microarrays.