Crystal structure of RIP1 kinase in complex with GSK3145095
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Crystal structure of RIP1 kinase in complex with GSK3145095 Descriptor: Receptor-interacting serine/threonine-protein kinase 1, ~{N}-[(3~{S})-7,9-bis(fluoranyl)-2-oxidanylidene-1,3,4,5-tetrahydro-1-benzazepin-3-yl]-3-(phenylmethyl)-1~{H}-1,2,4-triazole-5-carboxamide Authors: Thorpe, J.H, Harris, P.A. Deposit date: 2019-05-02 Release date: 2019-07-03 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.87 Å) Cite: Identification of a RIP1 Kinase Inhibitor Clinical Candidate (GSK3145095) for the Treatment of Pancreatic Cancer. Acs Med.Chem.Lett., 10, 2019
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2019-05-02
