MiRNA Profiling of Colorectal Tumors by Next Generation Sequencing. MiRNA Profiling of Colorectal Tumors by Next Generation Sequencing

Colorectal tumors have an impaired gene expression. As microRNAs (miRNAs) are involved in post-transcriptional regulation of gene expression we performed high-troughput miRNA profiling of 20 Adenomatous Polyp, 20 CRC and 32 healthy control formalin-fixed and paraffin-embedded samples using small RNA sequencing approach. Overall design: MiRNA profiling of colorectal cancer, adenomatous polyps and healthy colon fresh-frozen biopsy samples